WebRocuronium Non-depolarizing agent (defasciculating) 1.2 mg/kg IV (IBW) 70kg = 84 mg 1-2 min 45-70 minutes Difficult airway No major side effects Liver disease prolonged effect *Note that prolonged immobility and denervating neuromuscular disease leads to up-regulation of acetylcholine receptors. This can Web7 Dec 2024 · Recognition of rocuronium-induced anaphylaxis is often challenging, owing to its diverse clinical manifestations. Regarding treatment, several reports have described the efficacy of sugammadex, while conflicting reports have also been published. A 71-year-old man was scheduled to undergo split-thickness skin grafting surgery on his hip. During the …
Skin Testing to Identify Safe Drugs for Patients with Rocuronium ...
Web9 May 2024 · Median doses of rocuronium were 1.19 mg.kg −1 and 1.5 mg.kg −1 of succinylcholine. Herbstritt et al. performed a short review looking at use of equivalent doses of rocuronium and succinylcholine (1 mg.kg −1) for rapid sequence intubation 70. They included seven papers of varying quality (retrospective review, RCT and meta-analysis), … WebData demonstrating an association between failure to reverse neuromuscular blockade and adverse postoperative outcomes are less certain. A large case–control database investigation revealed that the primary anesthetic management characteristic associated with a reduction in mortality and coma was reversal of the effects of NMBAs. 13 In a … griffinshaws
Prolonged onset and duration of action of rocuronium after …
Rocuronium bromide (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation. It is used for standard endotracheal intubation, as well as for rapid sequence induct… Web30 Oct 2013 · A 0.6 mg/kg dose of rocuronium reached 80% recovery around 30 minutes, but took greater than 1 hour to recover 100%. What’s surprising to me was their findings comparing low dose rocuronium and 1.0 mg/kg of succinylcholine. The low dose rocuronium was around 5 minutes faster to reach 80%recover, and was at 100% recovery, … Web8 Oct 2024 · Among patients who develop anaphylaxis during anesthesia, anaphylaxis caused by a neuromuscular blocking agent has the highest incidence. In patients who developed IgE-mediated anaphylaxis, and cross-reactivity among NMBAs is a concern in subsequent anesthetic procedures. We present a patient who developed rocuronium … griffin shaw heacham