Webcausative role of oxygen radicals, nitric oxide, and peroxynitrite in human physiology and pathology. These aspects of human redox biochemistry contribute to the understanding … WebAs a consequence, peroxynitrite(1 mM)-induced H 2 O 2 formation (;80 mM at pH 7.5) also occurred under hy-poxic conditions. In the presence of bicarbonate/carbon dioxide (20 mM/5%) the production of H 2 O 2 from the re-action of HEPES with peroxynitrite was even further stimulated. Addition of SIN-1 or authentic peroxynitrite

Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro ...

WebDec 24, 1996 · Peroxynitrite activates the cyclooxygenase activities of constitutive and inducible prostaglandin endoperoxide synthases by serving as a substrate for the enzymes’ peroxidase activities. Activation of purified enzyme is induced by direct addition of peroxynitrite or by in situgeneration of peroxynitrite from NO coupling to superoxide anion. WebFeb 20, 1999 · Peroxynitrite was infused to maintain a 0.2 μM steady-state concentration in potassium phosphate buffer (pH 7.4). Benzoate hydroxylation and nitrite formation were … hipaa the privacy rule

Rapid peroxynitrite reduction by human peroxiredoxin 3

WebFeb 1, 2008 · In turn, reduction of peroxynitrite by peroxiredoxin 3 has been inferred from its protective actions against tyrosine nitration and neurotoxicity in animal models, but was … WebPeroxynitrite reduction by Plasmodium falciparum thioredoxin peroxidase 1 (PfTPx1) measured by an initial rate approach. (A) Initial rates of peroxynitrite (20 μM) decay in 50 … WebIn turn, reduction of peroxynitrite by peroxiredoxin 3 has been inferred from its protective actions against tyrosine nitration and neurotoxicity in animal models, but was not … hipaa tiered penalty structure