WebApr 26, 2024 · Most remain trapped at the plasma membrane or in intracellular compartments and do not reach their targets in the cytosol. Cytosolic arrival, via direct translocation across the plasma membrane or endocytosis followed by endosomal escape, is currently one of the main bottlenecks for the development of new macromolecular … WebJan 17, 2013 · However, the exact mechanism by which CaM mediates sorting and translocation of the small secretory proteins into the ER is largely unknown. Protein import into chloroplasts and mitochondria occurs posttranslationally. Similar to ER targeting, cytosolic factors are likely to be involved in the protein import into these endosymbiotic …
Late endosomes promote microglia migration via …
WebDec 1, 2024 · Here, we demonstrate that late endosomes, a type of prelysosomal organelles, facilitate actin-cytoskeleton remodeling via cytosolic translocation of immature protease cathepsin D (cathD) during... WebMar 16, 2024 · Here, we report a Ca 2+ signaling that controls photoreceptor phyB nuclear translocation in etiolated seedlings during dark-to-light transition. Red light stimulates … listview has been removed from react native
pH Sensing by Intracellular Salmonella Induces Effector …
WebHere, we present the synthetic multidomain peptide (named dTat-Sar-EED4) for cytosolic protein delivery in various plant species via simple peptide-protein coincubation. dTat-Sar-EED4 enabled the cytosolic delivery of an active enzyme with up to ∼20-fold greater efficiency than previously described cell-penetrating peptides in several model plant … WebDec 9, 2024 · Considering that enhancing potential cytosolic translocation evoked lamellipodia-distribution of cathD and increased cofilin activity (Fig. 4, G and H), we … WebJul 16, 2024 · The availability of intracellular, stabilized β-catenin, a transcription factor coactivator, is tightly regulated; β-catenin is translocated into the nucleus in response to Wnt ligand binding to its cell membrane receptors. Here we show that Wnt signal activation in mammalian cells activates intracellular mobilization of connexin 43 (Cx43), which … listview get selected item wpf