Cisplatin salt wasting
WebOct 6, 2016 · In the clinical setting, the most common and important manifestation of cisplatin nephrotoxicity is AKI, which can be progressive and even irreversible. Other renal manifestations include hypomagnesaemia, salt wasting, a … WebWe diagnosed this clinical condition as renal salt-wasting syndrome (RSWS) on the basis of dehydration and high urinary sodium excretion at the onset. In the second course of chemotherapy, CDDP was replaced with carboplatin (CBDCA); consequently, hyponatremia was not observed.
Cisplatin salt wasting
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WebCisplatin is known to induce Fanconi syndrome and renal salt wasting (RSW). RSW typically only requires transient normal saline (NS) support. We report a severe RSW case that required 12 liters of 3% saline. A 57-year-old woman with limited stage small cell cancer was admitted for cisplatin (80 mg/m 2) and etoposide (100 mg/m 2) therapy. WebCisplatin is an intercalating agent that induces apoptosis of cancer cells, and it has been the most widely used drug in the first-line chemotherapy. However, the increase in cisplatin-resistant cancer cells has become a major obstacle in clinical management of cancers (Amable, 2016 ).
WebNov 1, 2003 · In 1988, Hutchison et al reported profound urinary sodium wasting in 7 of 70 patients treated with cisplatin over an 18- month period in 1 institution. 1 All the patients were men with carcinomas (including 1 patient with SCLC) and presented 2-4 months after starting cisplatin-based therapy with signs of vol- ume depletion, urinary salt wasting ... WebAug 1, 2024 · Cisplatin (CDDP) is an important anticancer drug. A common side effect of CDDP is renal salt and water-wasting syndrome (RSWS). The origin of RSWS is …
WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head ... both water restrictions and sodium supplementation may be … WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head ... both water restrictions and sodium supplementation may be appropriate when differentiating between diagnoses of renal salt wasting syndrome and syndrome of inappropriate antidiuretic hormone secretion. Fed Pract. 2024 December;38(12 ...
WebSep 1, 2002 · (6) The mechanism of cisplatin-induced hyponatremia is thought to be mainly renal salt wasting syndrome (RSWS), (7) (8) (9) (10) (11) (12) (13) and sometimes the syndrome of inappropriate...
WebCisplatin Induced Renal Salt Wasting Syndrome: An Uncommon Diagnostic Distinction Session Information. Fluid, Electrolyte, and Acid-Base Disorders: Case Reports ... and recovery is the rule although recurrence is common. While carboplatin is less toxic, cisplatin has unequivocal superiority in most of the cancers in which it is used, making it ... how to stuff a tomatoWebFeb 16, 2024 · severe or ongoing nausea and vomiting; vision problems, pain behind your eyes; hearing problems, ringing in your ears; pain, redness, swelling, or skin … how to stuff a turkey crown recipeWebDec 10, 2024 · A 20-year-old man developed renal salt wasting syndrome (RSWS) during treatment with cisplatin for germ cell testicular cancer. The man had non-seminomatous … reading family shelf sculptureWebMay 19, 2024 · Rarely, cisplatin-related hyponatremia may result from Renal Salt Wasting Syndrome ( 33 ). Hypernatremia can also develop with cisplatin due to acquired nephrogenic diabetes insipidus with ensuing … how to stuff a sofa cushionWebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, … reading fair projects for 7th gradeWebBoth renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for … how to stuff a turkey safelyWebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular filtration, Fanconi syndrome, and renal tubular acidosis, nephrogenic diabetes insipidus and renal salt wasting syndrome. reading fan curves